Bioresorbable polymeric scaffolds for coronary revascularization: Lessons learnt from ABSORB III, ABSORB China, and ABSORB Japan

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Bioresorbable polymeric scaffolds for coronary revascularization: Lessons learnt from ABSORB III, ABSORB China, and ABSORB Japan

Bioresorbable polymers and biocorrodible metals are the latest developments in biodegradable materials used in interventional cardiology for the mechanical treatment of coronary atherosclerosis. Poly-L-lactic acid is the most frequently used bioresorbable polymer and initial evidence of feasibility, efficacy and clinical safety following deployment of polymer-based platforms was gained after co...

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Bioresorbable Vascular Scaffolds Versus Metallic Stents in Patients With Coronary Artery Disease: ABSORB China Trial.

BACKGROUND The everolimus-eluting bioresorbable vascular scaffold (BVS) is designed to achieve results comparable to metallic drug-eluting stents at 1 year, with improved long-term outcomes. Whether the 1-year clinical and angiographic results of BVS are noninferior to current-generation drug-eluting stents has not been established. OBJECTIVES This study sought to evaluate the angiographic ef...

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Absorb Bioresorbable Vascular Scaffold in Complex Coronary Bifurcation Interventions

Treatment of coronary bifurcation lesions is common in everyday practice and accounts for ≤20% of all percutaneous coronary interventions. The treatment of these lesions with drug-eluting stents, especially when a double-stent technique is used, remains challenging and is associated with a lower procedural success and a higher rate of long-term adverse cardiac events such as stent restenosis an...

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Three-Year Outcomes With the Absorb Bioresorbable Scaffold: Individual-Patient-Data Meta-Analysis From the ABSORB Randomized Trials.

BACKGROUND The Absorb bioresorbable vascular scaffold (BVS) completely resorbs within 3 years after coronary artery implantation. The safety and effectiveness of BVS through this critical 3-year period have not been characterized. METHODS We performed an individual-patient-data pooled meta-analysis of the 4 randomized ABSORB trials in which 3389 patients with coronary artery disease were rand...

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The absorb bioresorbable vascular scaffold in coronary bifurcations: insights from bench testing.

OBJECTIVES This study sought to evaluate the feasibility of performing contemporary bifurcation techniques with the Absorb everolimus-eluting bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, California) (BVS). BACKGROUND The feasibility of using the BVS in bifurcation lesions is unknown. METHODS We performed bifurcation stenting procedures including main-vessel stenting with b...

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ژورنال

عنوان ژورنال: Global Cardiology Science and Practice

سال: 2015

ISSN: 2305-7823

DOI: 10.5339/gcsp.2015.62